conessine


SMILES CN([C@H]1CC[C@]2(C(=CC[C@@H]3[C@@H]2CC[C@]24[C@H]3CC[C@@H]4[C@@H](N(C2)C)C)C1)C)C
InChIKey GPLGAQQQNWMVMM-MYAJQUOBSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 1
Molecular weight (Da) 356.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H1 HRH1 Human Histamine A pKi 5.0 5.0 5.0 Guide to Pharmacology
H2 HRH2 Human Histamine A pKi 5.0 5.0 5.0 Guide to Pharmacology
H3 HRH3 Human Histamine A pKi 8.3 8.3 8.3 Guide to Pharmacology
H4 HRH4 Human Histamine A pKi 5.0 5.0 5.0 Guide to Pharmacology
H3 HRH3 Rat Histamine A pKi 7.18 7.59 7.91 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 6.18 6.18 6.18 ChEMBL
H3 HRH3 Human Histamine A pKi 8.27 8.31 8.46 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 7.97 7.97 7.98 ChEMBL
H3 HRH3 Guinea pig Histamine A pKd 6.55 6.55 6.55 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
TSH TSHR Human Glycoprotein hormone A Potency 5.6 5.6 5.6 ChEMBL