CHEMBL1090813


SMILES C[C@H]1CN(C(=O)[C@@H]2CN(C(C)(C)C)C[C@H]2c2ccc(F)cc2F)C[C@@H](C)[C@]1(O)c1ccc(F)cc1F
InChIKey KUBVRBHREBOZQR-JNXJTYLLSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 506.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC4 MC4R Human Melanocortin A pKi 6.75 6.75 6.75 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC1 MSHR Human Melanocortin A pEC50 5.18 5.18 5.18 ChEMBL
MC5 MC5R Human Melanocortin A pEC50 5.46 5.46 5.46 ChEMBL
MC3 MC3R Human Melanocortin A pEC50 4.97 4.97 4.97 ChEMBL
MC4 MC4R Human Melanocortin A pEC50 7.21 7.21 7.21 ChEMBL