CP 154,526
| SMILES | CCCCN(c1nc(C)nc2c1c(C)cn2c1c(C)cc(cc1C)C)CC |
| InChIKey | FHQYJZCJRZHINA-UHFFFAOYSA-N |
Chemical properties
| Hydrogen bond acceptors | 4 |
| Hydrogen bond donors | 0 |
| Rotatable bonds | 6 |
| Molecular weight (Da) | 364.3 |
Drug properties
| Molecular type | Small molecule |
| Physiological/Surrogate | Surrogate |
| Approved drug | No |
Database connections
Sankey plot
Compound is not listed as a drug.
Bioactivities
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| CRF1 | CRFR1 | Human | Corticotropin-releasing factor | B1 | pKi | 7.25 | 8.48 | 8.8 | ChEMBL |
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| CRF1 | CRFR1 | Rat | Corticotropin-releasing factor | B1 | pIC50 | 9.29 | 9.85 | 10.41 | Guide to Pharmacology |
| CRF1 | CRFR1 | Rat | Corticotropin-releasing factor | B1 | pIC50 | 8.26 | 8.26 | 8.26 | ChEMBL |
| CRF1 | CRFR1 | Human | Corticotropin-releasing factor | B1 | pIC50 | 7.8 | 7.88 | 7.96 | ChEMBL |