CHEMBL212766


SMILES CC(=O)N[C@H](Cc1ccccc1)C(=O)N1C[C@H](OCc2ccc3ccccc3c2)C[C@@H]1CCCN=C(N)N
InChIKey WIUGVXOSBXINHH-UPRLRBBYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 11
Molecular weight (Da) 515.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC1 MSHR Human Melanocortin A pKi 6.33 6.33 6.33 ChEMBL
MC3 MC3R Human Melanocortin A pKi 6.54 6.54 6.54 ChEMBL
MC4 MC4R Human Melanocortin A pKi 7.05 7.05 7.05 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC1 MSHR Human Melanocortin A pEC50 6.63 6.63 6.63 ChEMBL
MC3 MC3R Human Melanocortin A pEC50 5.86 5.86 5.86 ChEMBL
MC4 MC4R Human Melanocortin A pEC50 6.5 6.5 6.5 ChEMBL