CHEMBL214029


SMILES O=C(NCCC1CCNCC1)[C@H]1CCCN1C(=O)[C@@H]1C[C@@H](O)CN1C(=O)CC(c1ccc(F)cc1)(c1ccc(F)cc1)c1ccc(F)cc1
InChIKey AIZMFPJJDXEQKC-SXLOSVNLSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 3
Rotatable bonds 10
Molecular weight (Da) 676.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 7.54 7.54 7.54 ChEMBL
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 9.32 9.32 9.32 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 6.66 6.66 6.66 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 6.52 6.52 6.52 ChEMBL
M5 ACM5 Human Acetylcholine (muscarinic) A pKi 5.77 5.77 5.77 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database