GPCRdb

CHEMBL213122

Agent/drug
Bioactivity

CHEMBL213122

SMILES	Cc1ccc(N2CCN(C(=O)[C@H](C)Cc3ccc(Cl)cc3)CC2)c([C@@H](N)CC(C)C)c1
InChIKey	RZLPZBLBQNNVLZ-YKSBVNFPSA-N

Chemical Properties

Hydrogen bond acceptors	3
Hydrogen bond donors	1
Rotatable bonds	7
Molecular weight (Da)	441.3

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

MC₁	MSHR	Human	Melanocortin	A	pKi	5.51	5.51	5.51	ChEMBL
MC₃	MC3R	Human	Melanocortin	A	pKi	5.89	5.89	5.89	ChEMBL
MC₄	MC4R	Human	Melanocortin	A	pKi	7.60	7.60	7.60	ChEMBL
MC₅	MC5R	Human	Melanocortin	A	pKi	6.00	6.00	6.00	ChEMBL

Showing 1 to 4 of 4 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

MC₄	MC4R	Human	Melanocortin	A	pIC50	6.24	6.25	6.25	ChEMBL

Showing 1 to 1 of 1 entry

CHEMBL213122

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.