CXCR4 antagonist 22


SMILES Clc1ccccc1CN1CCC(CC1)CNCc1cccc(c1)c1ccccc1
InChIKey XBEBHNXBLIDZDS-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 404.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CXCR4 CXCR4 Human Chemokine A pIC50 5.6 6.0 6.3 ChEMBL
CXCR4 CXCR4 Human Chemokine A pIC50 6.3 6.3 6.3 Guide to Pharmacology