CHEMBL202699


SMILES CNC(=O)[C@H](Cc1ccc2ccccc2c1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccc(O)cc1)NC(C)=O
InChIKey QVTMGASDQFBYLJ-AYXCPNKJSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 8
Rotatable bonds 18
Molecular weight (Da) 736.4

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC1 MSHR Human Melanocortin A pKi 5.34 5.34 5.34 ChEMBL
MC3 MC3R Human Melanocortin A pKi 5.76 5.76 5.76 ChEMBL
MC4 MC4R Human Melanocortin A pKi 6.98 6.98 6.98 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC1 MSHR Human Melanocortin A pEC50 4.7 4.7 4.7 ChEMBL
MC3 MC3R Human Melanocortin A pEC50 4.7 4.7 4.7 ChEMBL
MC4 MC4R Human Melanocortin A pEC50 7.36 7.36 7.36 ChEMBL