CHEMBL2164354


SMILES O=C(C1CCCCC1)N(CCN1CC=C(c2ccccc2)CC1)c1ccccn1
InChIKey YUOLKUGHNOWKJF-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 389.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1B ADA1B Human Adrenoceptors A pKi 6.53 6.53 6.53 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 7.41 7.41 7.41 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.22 7.22 7.22 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.98 6.98 6.98 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.42 6.84 7.26 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 9.16 9.22 9.29 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.27 7.27 7.27 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database