GPCRdb

CHEMBL2165137

Agent/drug
Bioactivity

CHEMBL2165137

SMILES	Clc1cccc(C2CCN(CCCCOc3ccc4scnc4c3)CC2)c1Cl
InChIKey	DXXXGJIMFKZHRL-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	4
Hydrogen bond donors	0
Rotatable bonds	7
Molecular weight (Da)	434.1

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

5-HT_1A	5HT1A	Human	5-Hydroxytryptamine	A	pKi	9.22	9.22	9.22	ChEMBL
5-HT_2A	5HT2A	Human	5-Hydroxytryptamine	A	pKi	9.22	9.22	9.22	ChEMBL
5-HT_2B	5HT2B	Human	5-Hydroxytryptamine	A	pKi	9.22	9.22	9.22	ChEMBL
5-HT_2C	5HT2C	Human	5-Hydroxytryptamine	A	pKi	9.22	9.22	9.22	ChEMBL
D₂	DRD2	Human	Dopamine	A	pKi	7.38	7.38	7.38	ChEMBL

Showing 1 to 5 of 5 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

D₂	DRD2	Human	Dopamine	A	pEC50	7.09	7.29	7.68	ChEMBL

Showing 1 to 1 of 1 entry

CHEMBL2165137

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.