CHEMBL2037289


SMILES Cc1ccc2nc(-c3cccc(C[C@H](O)/C=C/[C@H]4CCC(=O)N4CCSc4nc(C(=O)O)cs4)c3)oc2c1
InChIKey JUFYXGLEONTECM-KSFASEQNSA-N

Chemical properties

Hydrogen bond acceptors 8
Hydrogen bond donors 2
Rotatable bonds 10
Molecular weight (Da) 549.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP1 PE2R1 Mouse Prostanoid A pKi 6.7 6.7 6.7 ChEMBL
EP2 PE2R2 Mouse Prostanoid A pKi 7.25 7.25 7.25 ChEMBL
EP4 PE2R4 Mouse Prostanoid A pKi 9.8 9.8 9.8 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP2 PE2R2 Rat Prostanoid A pEC50 5.5 5.5 5.5 ChEMBL
EP4 PE2R4 Rat Prostanoid A pEC50 8.8 8.8 8.8 ChEMBL