dimethylhistaprodifen
| SMILES | CN(CCc1cnc([nH]1)CCC(c1ccccc1)c1ccccc1)C |
| InChIKey | GNBOIGBQIBQOIA-UHFFFAOYSA-N |
Chemical properties
| Hydrogen bond acceptors | 2 |
| Hydrogen bond donors | 1 |
| Rotatable bonds | 8 |
| Molecular weight (Da) | 333.2 |
Drug properties
| Molecular type | Small molecule |
| Physiological/Surrogate | Surrogate |
| Approved drug | No |
Database connections
Sankey plot
Compound is not listed as a drug.
Bioactivities
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| β1 | B0FL73 | Guinea pig | Adrenoceptors | A | pKd | 4.58 | 4.58 | 4.58 | ChEMBL |
| H1 | HRH1 | Guinea pig | Histamine | A | pKd | 7.98 | 8.64 | 9.11 | ChEMBL |
| H1 | HRH1 | Human | Histamine | A | pKi | 6.4 | 6.4 | 6.4 | Guide to Pharmacology |
| α1D | ADA1D | Rat | Adrenoceptors | A | pKd | 5.11 | 5.11 | 5.11 | ChEMBL |
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| H1 | HRH1 | Rat | Histamine | A | pEC50 | 6.77 | 6.77 | 6.77 | ChEMBL |
| H1 | HRH1 | Guinea pig | Histamine | A | pEC50 | 6.08 | 6.69 | 7.08 | ChEMBL |