dipropyl-5-CT


SMILES CCCN(CCC)CCc1c[nH]c2c1cc(cc2)C(=O)N
InChIKey DPXOFRGRKPFZOD-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 2
Rotatable bonds 8
Molecular weight (Da) 287.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Ligand site mutations 5-HT1B 5-HT6

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 7.4 7.4 7.4 Guide to Pharmacology
5-HT1F 5HT1F Human 5-Hydroxytryptamine A pKi 5.8 5.8 5.8 Guide to Pharmacology
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 8.2 8.3 8.4 Guide to Pharmacology
5-HT1D F1MMU1 Bovine 5-Hydroxytryptamine A pKi 6.92 7.16 7.24 PDSP Ki database
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 7.38 7.63 7.89 PDSP Ki database
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 7.38 7.63 7.89 PDSP Ki database
5-HT2A 5HT2A Rat 5-Hydroxytryptamine A pKi 5.0 5.0 5.0 PDSP Ki database
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.29 6.29 6.29 PDSP Ki database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.3 6.3 6.3 PDSP Ki database
5-HT2C 5HT2C Rat 5-Hydroxytryptamine A pKi 5.0 5.0 5.0 PDSP Ki database
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.0 6.0 6.0 PDSP Ki database
5-HT7 5HT7R Guinea pig 5-Hydroxytryptamine A pKi 7.87 8.07 8.27 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pIC50 7.9 7.9 7.9 Guide to Pharmacology
M1 ACM1 Rat Acetylcholine (muscarinic) A Potency 4.7 4.75 4.8 ChEMBL