CHEMBL2179654


SMILES CN1CC[C@]23c4c5ccc(O)c4O[C@H]2c2ncc(-c4ccc(Cl)cc4)cc2C[C@@]3(OCc2ccccc2)[C@H]1C5
InChIKey YYSCTYIWGJPHIQ-OUDZLNJNSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 536.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections


Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 8.75 8.75 8.75 ChEMBL
κ OPRK Human Opioid A pKi 7.31 7.31 7.31 ChEMBL
μ OPRM Human Opioid A pKi 8.33 8.33 8.33 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pEC50 7.96 7.96 7.96 ChEMBL
κ OPRK Human Opioid A pEC50 6.67 6.67 6.67 ChEMBL
μ OPRM Human Opioid A pEC50 6.52 6.52 6.52 ChEMBL