DR-4004


SMILES O=C1Nc2c3C1(CCCCN1CCC(=CC1)c1ccccc1)CCCc3ccc2
InChIKey JBQOYPLKTTXLSQ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 386.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Rat 5-Hydroxytryptamine A pKi 7.3 7.3 7.3 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 8.48 8.66 8.7 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.77 6.77 6.77 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.28 6.28 6.28 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 8.7 8.7 8.7 Guide to Pharmacology
D2 DRD2 Rat Dopamine A pKi 6.98 6.98 6.98 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database