GPCRdb

CHEMBL217999

Agent/drug
Bioactivity

CHEMBL217999

SMILES	Cc1ccc(CN2CCN3C[C@H](C)[C@](C)(c4cccc(O)c4)C[C@@H]3C2)cc1
InChIKey	ZWDRGROQJMUOOH-BPUDTRNYSA-N

Chemical Properties

Hydrogen bond acceptors	3
Hydrogen bond donors	1
Rotatable bonds	3
Molecular weight (Da)	364.3

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

δ	OPRD	Human	Opioid	A	pKi	6.46	6.46	6.46	ChEMBL
κ	OPRK	Human	Opioid	A	pKi	6.52	6.52	6.52	ChEMBL
μ	OPRM	Human	Opioid	A	pKi	7.85	7.85	7.85	ChEMBL

Showing 1 to 3 of 3 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

μ	OPRM	Human	Opioid	A	pIC50	8.02	8.02	8.02	ChEMBL

Showing 1 to 1 of 1 entry

CHEMBL217999

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.