dynorphin A-(1-13)


SMILES None
InChIKey OVVIBUHLQIYUEU-IWIISZHXSA-N
Sequence YGGFLRRIRPKLK

Chemical properties

Hydrogen bond acceptors None
Hydrogen bond donors None
Rotatable bonds None
Molecular weight (Da)

Drug properties

Molecular type Peptide
Physiological/Surrogate Endogenous
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Human Opioid A pKi 9.3 10.0 10.7 Guide to Pharmacology
μ OPRM Human Opioid A pKi 8.3 8.3 8.3 Guide to Pharmacology
κ OPRK Rat Opioid A pKi 9.9 9.9 9.9 Guide to Pharmacology
κ OPRK Rat Opioid A pKi 8.47 8.94 9.22 ChEMBL
κ OPRK Guinea pig Opioid A pKi 8.44 8.97 9.51 ChEMBL
δ OPRD Human Opioid A pKi 7.55 7.99 8.42 ChEMBL
κ OPRK Human Opioid A pKi 9.64 9.85 10.05 ChEMBL
μ OPRM Human Opioid A pKi 8.1 8.1 8.1 ChEMBL
δ OPRD Human Opioid A pKi 7.8 7.8 7.8 Guide to Pharmacology
μ OPRM Rat Opioid A pKi 8.4 8.4 8.4 ChEMBL
κ OPRK Mouse Opioid A pKi 9.52 9.52 9.52 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Rat Opioid A pEC50 7.75 8.02 8.22 ChEMBL
δ OPRD Mouse Opioid A pIC50 8.04 8.12 8.2 ChEMBL
κ OPRK Guinea pig Opioid A pIC50 9.94 9.94 9.94 ChEMBL
κ OPRK Guinea pig Opioid A pEC50 7.75 7.75 7.75 ChEMBL
δ OPRD Human Opioid A pIC50 8.39 8.39 8.39 ChEMBL
δ OPRD Human Opioid A pEC50 7.73 7.73 7.73 ChEMBL
κ OPRK Human Opioid A pIC50 9.83 9.83 9.83 ChEMBL
κ OPRK Human Opioid A pEC50 7.4 8.19 8.82 ChEMBL
μ OPRM Human Opioid A pEC50 6.67 6.67 6.67 ChEMBL
κ OPRK Mouse Opioid A pEC50 6.8 7.48 8.17 ChEMBL