dynorphin A-(1-8)


SMILES None
InChIKey WRPLGMBDXVBPEG-VGXZEHLRSA-N
Sequence YGGFLRRI

Chemical properties

Hydrogen bond acceptors None
Hydrogen bond donors None
Rotatable bonds None
Molecular weight (Da)

Drug properties

Molecular type Peptide
Physiological/Surrogate Endogenous
Approved drug No

Database connections

Structure pdb 7Y1F 8F7W

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pKi 8.4 8.4 8.4 Guide to Pharmacology
μ OPRM Human Opioid A pKi 8.4 8.4 8.4 Guide to Pharmacology
μ OPRM Human Opioid A pKi 7.45 7.45 7.45 ChEMBL
δ OPRD Human Opioid A pKi 8.07 8.07 8.07 ChEMBL
κ OPRK Human Opioid A pKi 8.34 8.34 8.34 ChEMBL
κ OPRK Human Opioid A pKi 8.0 8.95 9.9 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Mouse Opioid A pIC50 9.7 9.7 9.7 Guide to Pharmacology