EFPPEA
| SMILES | CCc1nn2c(c1CCNC(=O)C)c1CCOc1cc2 |
| InChIKey | IZDHETWMKYCGAU-UHFFFAOYSA-N |
Chemical properties
| Hydrogen bond acceptors | 4 |
| Hydrogen bond donors | 1 |
| Rotatable bonds | 4 |
| Molecular weight (Da) | 273.1 |
Drug properties
| Molecular type | Small molecule |
| Physiological/Surrogate | Surrogate |
| Approved drug | No |
Database connections
Sankey plot
Compound is not listed as a drug.
Bioactivities
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| MT1 | MTR1A | Human | Melatonin | A | pKi | 10.2 | 10.2 | 10.2 | Guide to Pharmacology |
| MT2 | MTR1B | Human | Melatonin | A | pKi | 9.4 | 9.4 | 9.4 | Guide to Pharmacology |
| MT2 | MTR1B | Human | Melatonin | A | pKi | 9.38 | 9.38 | 9.38 | ChEMBL |
| MT1 | MTR1A | Human | Melatonin | A | pKi | 10.21 | 10.21 | 10.21 | ChEMBL |
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| MT2 | MTR1B | Human | Melatonin | A | pEC50 | 9.28 | 9.28 | 9.28 | ChEMBL |
| MT1 | MTR1A | Human | Melatonin | A | pEC50 | 10.68 | 10.68 | 10.68 | ChEMBL |