CHEMBL220515


SMILES COc1ccc(Cl)cc1N1CCN(CCn2c(C)nc3c([nH]c4ccccc43)c2=O)CC1
InChIKey AMDQVJAWEJXJFN-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 451.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1B ADA1B Human Adrenoceptors A pKi 8.35 8.35 8.35 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 8.88 8.88 8.88 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 9.78 9.78 9.78 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database