EMD-386088


SMILES Clc1ccc2c(c1)c(C1=CCNCC1)c([nH]2)C
InChIKey BPPGPYJBCVXILI-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 1
Hydrogen bond donors 2
Rotatable bonds 1
Molecular weight (Da) 246.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1B 5HT1B Rat 5-Hydroxytryptamine A pIC50 6.75 6.75 6.75 ChEMBL
5-HT4 5HT4R Guinea pig 5-Hydroxytryptamine A pIC50 6.21 6.21 6.21 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pIC50 5.52 5.52 5.52 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pIC50 6.18 6.18 6.18 ChEMBL
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pIC50 6.96 6.96 6.96 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pIC50 6.62 6.62 6.62 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pIC50 6.35 6.35 6.35 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pIC50 8.13 8.13 8.13 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pIC50 8.13 8.13 8.13 Guide to Pharmacology