CHEMBL1093735


SMILES Cc1ccc(C(c2ccc(Cl)cc2Cl)N2CCN(C(=O)NC3CCCCC3)CC2)cc1
InChIKey LRFGNVCBHZJPNK-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 459.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections


Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CB2 CNR2 Human Cannabinoid A pKi 6.48 6.48 6.48 ChEMBL
CB1 CNR1 Human Cannabinoid A pKi 9.82 9.82 9.82 ChEMBL
CB1 CNR1 Human Cannabinoid A pKi 9.82 9.82 9.82 PDSP Ki database
CB2 CNR2 Human Cannabinoid A pKi 6.48 6.48 6.48 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CB1 CNR1 Human Cannabinoid A pEC50 9.06 9.06 9.06 ChEMBL
CB1 CNR1 Human Cannabinoid A pIC50 8.57 8.57 8.57 ChEMBL