CHEMBL2207639


SMILES COc1ccccc1N1CCN(Cc2cc(CN3CCOCC3)c3cccccc2-3)CC1
InChIKey RMDQSWIVOHIFNT-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 431.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2A 5HT2A Pig 5-Hydroxytryptamine A pKi 6.0 6.0 6.0 ChEMBL
D1 DRD1 Pig Dopamine A pKi 5.3 5.3 5.3 ChEMBL
H2 HRH2 Human Histamine A pKi 5.21 5.21 5.21 ChEMBL
H1 HRH1 Human Histamine A pKi 5.19 5.19 5.19 ChEMBL
D4 DRD4 Human Dopamine A pKi 8.34 8.34 8.34 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.46 6.46 6.46 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.89 6.96 7.04 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database