eticlopride


SMILES CCN1CCC[C@H]1CNC(=O)c1c(O)c(CC)cc(c1OC)Cl
InChIKey AADCDMQTJNYOSS-LBPRGKRZSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 6
Molecular weight (Da) 340.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug Yes

Database connections

Structure pdb 3PBL
Ligand site mutations D1 D2 D3 D4

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Human Dopamine A pKi 9.2 9.2 9.2 Guide to Pharmacology
D3 DRD3 Human Dopamine A pKi 8.8 8.8 8.8 Guide to Pharmacology
D4 DRD4 Human Dopamine A pKi 7.0 7.0 7.0 Guide to Pharmacology
D2 DRD2 Rat Dopamine A pKd 9.77 9.77 9.77 ChEMBL
D2 DRD2 Rat Dopamine A pKi 9.0 9.67 10.05 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.15 7.15 7.15 ChEMBL
D3 DRD3 Human Dopamine A pKi 9.8 9.9 9.97 ChEMBL
D2 DRD2 Human Dopamine A pKi 9.59 9.86 10.07 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Rat Dopamine A pIC50 9.04 9.04 9.04 ChEMBL