CHEMBL221183


SMILES CC1(C)COc2c(OCCNCc3cccc(C4=CCCC4)c3)cccc21
InChIKey MXPWGHGCCKQDEC-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 363.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections


Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Rat Dopamine A pKi 9.09 9.09 9.09 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 7.37 7.37 7.37 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pEC50 6.95 6.95 6.95 ChEMBL