famotidine


SMILES NC(=Nc1scc(n1)CSCC/C(=N/S(=O)(=O)N)/N)N
InChIKey XUFQPHANEAPEMJ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 4
Rotatable bonds 7
Molecular weight (Da) 337.0

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug Yes

Database connections

Structure pdb 7UL3

Sankey plot

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H2 HRH2 Human Histamine A pKi 7.39 7.39 7.39 ChEMBL
H2 HRH2 Guinea pig Histamine A pKi 7.92 7.92 7.92 PDSP Ki database
H2 HRH2 Human Histamine A pKd 8.1 8.1 8.1 Drug Central
H2 HRH2 Guinea pig Histamine A pKd 8.15 8.15 8.15 Drug Central
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H2 HRH2 Human Histamine A pIC50 7.38 7.38 7.38 ChEMBL
TSH TSHR Human Glycoprotein hormone A Potency 4.5 4.5 4.5 ChEMBL