GPCRdb

CHEMBL2208347

Agent/drug
Bioactivity

CHEMBL2208347

SMILES	C[C@H]1[C@H]2Cc3ccc(C(=O)NCCc4ccc(-c5ccc(O)cc5)cc4)cc3[C@]1(C)CCN2CC1CC1
InChIKey	FTRDSYLIWZRYMR-OAXZOYPSSA-N

Chemical Properties

Hydrogen bond acceptors	3
Hydrogen bond donors	2
Rotatable bonds	7
Molecular weight (Da)	494.3

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

δ	OPRD	Human	Opioid	A	pKi	9.11	9.11	9.11	ChEMBL
κ	OPRK	Human	Opioid	A	pKi	9.44	9.44	9.44	ChEMBL

Showing 1 to 2 of 2 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

δ	OPRD	Human	Opioid	A	pEC50	9.51	9.51	9.51	ChEMBL
κ	OPRK	Human	Opioid	A	pEC50	9.59	9.59	9.59	ChEMBL
μ	OPRM	Human	Opioid	A	pIC50	8.35	8.35	8.35	ChEMBL
μ	OPRM	Human	Opioid	A	pEC50	9.30	9.30	9.30	ChEMBL

Showing 1 to 4 of 4 entries

CHEMBL2208347

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.