GPCRdb

CHEMBL2208351

Agent/drug
Bioactivity

CHEMBL2208351

SMILES	CC1C2Cc3ccc(C(=O)NCCc4ccc(-c5ccc6c(c5)OCO6)cc4)cc3C1(C)CCN2CC1CC1
InChIKey	NFVWPZJBRDAYII-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	4
Hydrogen bond donors	1
Rotatable bonds	7
Molecular weight (Da)	522.3

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

δ	OPRD	Human	Opioid	A	pKi	9.00	9.00	9.00	ChEMBL
κ	OPRK	Human	Opioid	A	pKi	9.14	9.14	9.14	ChEMBL

Showing 1 to 2 of 2 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

δ	OPRD	Human	Opioid	A	pEC50	9.10	9.10	9.10	ChEMBL
κ	OPRK	Human	Opioid	A	pEC50	9.47	9.47	9.47	ChEMBL
μ	OPRM	Human	Opioid	A	pIC50	7.96	7.96	7.96	ChEMBL
μ	OPRM	Human	Opioid	A	pEC50	9.82	9.82	9.82	ChEMBL

Showing 1 to 4 of 4 entries

CHEMBL2208351

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.