GPCRdb

CHEMBL2208354

Agent/drug
Bioactivity

CHEMBL2208354

SMILES	COc1ccc2cc(CCNC(=O)c3ccc4c(c3)C3(C)CCN(CC5CC5)C(C4)C3C)ccc2c1
InChIKey	YIYFILGSLZRBRB-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	3
Hydrogen bond donors	1
Rotatable bonds	7
Molecular weight (Da)	482.3

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

δ	OPRD	Human	Opioid	A	pKi	8.66	8.66	8.66	ChEMBL
κ	OPRK	Human	Opioid	A	pKi	9.35	9.35	9.35	ChEMBL
μ	OPRM	Human	Opioid	A	pKi	10.19	10.19	10.19	ChEMBL

Showing 1 to 3 of 3 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

δ	OPRD	Human	Opioid	A	pEC50	8.12	8.12	8.12	ChEMBL
κ	OPRK	Human	Opioid	A	pEC50	8.89	8.89	8.89	ChEMBL
μ	OPRM	Human	Opioid	A	pIC50	7.35	7.35	7.35	ChEMBL

Showing 1 to 3 of 3 entries

CHEMBL2208354

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.