CHEMBL222677


SMILES Cc1cc(Cl)ccc1-c1cccc([C@H](O)CC[C@H]2CCC(=O)N2CCc2ccc(C(=O)O)cc2)c1
InChIKey DQBNEYSJJSAOQB-AHKZPQOWSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 9
Molecular weight (Da) 491.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP1 PE2R1 Human Prostanoid A pKi 4.75 4.75 4.75 ChEMBL
EP2 PE2R2 Human Prostanoid A pKi 5.29 5.29 5.29 ChEMBL
EP3 PE2R3 Human Prostanoid A pKi 4.27 4.27 4.27 ChEMBL
EP4 PE2R4 Human Prostanoid A pKi 9.03 9.03 9.03 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP4 PE2R4 Human Prostanoid A pEC50 10.4 10.4 10.4 ChEMBL