GPCRdb

CHEMBL221183

Agent/drug
Bioactivity

CHEMBL221183

SMILES	CC1(C)COc2c(OCCNCc3cccc(C4=CCCC4)c3)cccc21
InChIKey	MXPWGHGCCKQDEC-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	3
Hydrogen bond donors	1
Rotatable bonds	7
Molecular weight (Da)	363.2

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

5-HT_1A	5HT1A	Rat	5-Hydroxytryptamine	A	pKi	7.37	7.37	7.37	ChEMBL
D₂	DRD2	Rat	Dopamine	A	pKi	9.09	9.09	9.09	ChEMBL

Showing 1 to 2 of 2 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

5-HT_1A	5HT1A	Human	5-Hydroxytryptamine	A	pEC50	6.95	6.95	6.95	ChEMBL

Showing 1 to 1 of 1 entry

CHEMBL221183

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV 0

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.