GPCRdb

ADOPRAZINE

Agent/drug
Bioactivity

ADOPRAZINE

SMILES	Fc1ccc(-c2cncc(CN3CCN(c4cccc5c4OCCO5)CC3)c2)cc1
InChIKey	IUVSEUFHPNITEQ-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	5
Hydrogen bond donors	0
Rotatable bonds	4
Molecular weight (Da)	405.2

Database connections

ChEMBL_compound_ids ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

5-HT_1A	5HT1A	Rat	5-Hydroxytryptamine	A	pKi	8.64	8.64	8.64	ChEMBL
5-HT_1A	5HT1A	Human	5-Hydroxytryptamine	A	pKi	9.10	9.10	9.10	ChEMBL
5-HT_2A	5HT2A	Human	5-Hydroxytryptamine	A	pKi	6.60	6.60	6.60	ChEMBL
5-HT_2B	5HT2B	Human	5-Hydroxytryptamine	A	pKi	7.90	7.90	7.90	ChEMBL
5-HT₇	5HT7R	Human	5-Hydroxytryptamine	A	pKi	7.20	7.20	7.20	ChEMBL
D₂	DRD2	Rat	Dopamine	A	pKi	8.40	8.40	8.40	ChEMBL
D₂	DRD2	Human	Dopamine	A	pKi	8.40	8.40	8.40	ChEMBL
D₃	DRD3	Human	Dopamine	A	pKi	8.40	8.40	8.40	ChEMBL
D₄	DRD4	Human	Dopamine	A	pKi	8.00	8.00	8.00	ChEMBL

Showing 1 to 9 of 9 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

5-HT_1A	5HT1A	Human	5-Hydroxytryptamine	A	pEC50	8.23	8.23	8.23	ChEMBL

Showing 1 to 1 of 1 entry

ADOPRAZINE

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.