GPCRdb

REMOXIPRIDE

Agent/drug
Bioactivity

REMOXIPRIDE

SMILES	CCN1CCC[C@H]1CNC(=O)c1c(OC)ccc(Br)c1OC
InChIKey	GUJRSXAPGDDABA-NSHDSACASA-N

Chemical Properties

Hydrogen bond acceptors	4
Hydrogen bond donors	1
Rotatable bonds	6
Molecular weight (Da)	370.1

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

β₂	ADRB2	Rat	Adrenoceptors	A	pKi	5.00	5.00	5.00	PDSP Ki database
5-HT_1A	5HT1A	Human	5-Hydroxytryptamine	A	pKd	5.40	5.40	5.40	ChEMBL
5-HT_1A	5HT1A	Rat	5-Hydroxytryptamine	A	pKi	5.00	5.00	5.00	PDSP Ki database
5-HT_1A	5HT1A	Human	5-Hydroxytryptamine	A	pKi	5.16	5.16	5.16	PDSP Ki database
5-HT_1A	5HT1A	Human	5-Hydroxytryptamine	A	pKd	8.27	8.27	8.27	Drug Central
5-HT_1D	F1MMU1	Bovine	5-Hydroxytryptamine	A	pKi	5.21	5.21	5.21	PDSP Ki database
5-HT_2A	5HT2A	Human	5-Hydroxytryptamine	A	pKi	5.00	5.25	5.51	PDSP Ki database
5-HT_2A	5HT2A	Human	5-Hydroxytryptamine	A	pKi	8.26	8.26	8.26	Drug Central
5-HT_2C	5HT2C	Rat	5-Hydroxytryptamine	A	pKi	5.07	5.17	5.26	PDSP Ki database
5-HT₆	5HT6R	Mouse	5-Hydroxytryptamine	A	pKi	5.00	5.00	5.00	PDSP Ki database
5-HT₆	5HT6R	Rat	5-Hydroxytryptamine	A	pKi	5.30	5.30	5.30	PDSP Ki database
5-HT₆	5HT6R	Human	5-Hydroxytryptamine	A	pKi	5.30	5.30	5.30	PDSP Ki database
5-HT₇	5HT7R	Human	5-Hydroxytryptamine	A	pKi	4.44	4.44	4.44	PDSP Ki database
5-HT₇	5HT7R	Rat	5-Hydroxytryptamine	A	pKi	5.30	5.30	5.30	PDSP Ki database
D₁	DRD1	Rat	Dopamine	A	pKi	5.00	5.00	5.00	PDSP Ki database
D₂	DRD2	Green monkey	Dopamine	A	pKi	6.06	6.06	6.06	ChEMBL
D₂	DRD2	Human	Dopamine	A	pKi	6.05	7.02	7.80	PDSP Ki database
D₂	DRD2	Rat	Dopamine	A	pKi	5.69	6.07	7.27	PDSP Ki database
D₂	DRD2	Dog	Dopamine	A	pKi	6.52	6.52	6.52	PDSP Ki database
D₂	DRD2	Green monkey	Dopamine	A	pKi	8.22	8.22	8.22	Drug Central

Showing 1 to 20 of 30 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

D₂	DRD2	Rat	Dopamine	A	pIC50	5.80	5.82	5.85	ChEMBL
D₂	DRD2	Human	Dopamine	A	pIC50	6.06	7.49	8.92	ChEMBL
D₂	DRD2	Human	Dopamine	A	pIC50	8.22	8.22	8.22	Drug Central
D₂	DRD2	Rat	Dopamine	A	pIC50	8.23	8.23	8.23	Drug Central
D₄	DRD4	Human	Dopamine	A	pIC50	5.41	5.41	5.41	ChEMBL

Showing 1 to 5 of 5 entries

REMOXIPRIDE

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.