CHEMBL224730


SMILES C[n+]1c[nH]cc1C[C@H](N)C(=O)N1C(=O)CC[C@H]1C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N1CCC[C@H]1C(N)=O
InChIKey BLZYVFWTYKBEOQ-XSLAGTTESA-O

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 5
Rotatable bonds 9
Molecular weight (Da) 514.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
TRH1 TRFR Human Thyrotropin-releasing hormone A pKi 8.52 8.52 8.52 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
TRH1 TRFR Human Thyrotropin-releasing hormone A pEC50 8.3 8.3 8.3 ChEMBL