G-1


SMILES CC(=O)c1ccc2c(c1)[C@@H]1C=CC[C@@H]1[C@@H](N2)c1cc2OCOc2cc1Br
InChIKey VHSVKVWHYFBIFJ-HKZYLEAXSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 2
Molecular weight (Da) 411.0

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
GPER GPER1 Human Estrogen (G protein-coupled) A pKi 8.0 8.0 8.0 Guide to Pharmacology
GPER GPER1 Human Estrogen (G protein-coupled) A pKi 7.96 8.02 8.15 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
GPER GPER1 Human Estrogen (G protein-coupled) A pEC50 5.84 7.75 8.7 ChEMBL
GPER GPER1 Human Estrogen (G protein-coupled) A pIC50 7.96 7.96 7.96 ChEMBL