galanin


SMILES None
InChIKey CBSXZYWGVAQSHI-RUKUCZSXSA-N
Sequence GWTLNSAGYLLGPHAVGNHRSFSDKNGLTS

Chemical properties

Hydrogen bond acceptors None
Hydrogen bond donors None
Rotatable bonds None
Molecular weight (Da)

Drug properties

Molecular type Peptide
Physiological/Surrogate Endogenous
Approved drug No

Database connections

Structure pdb 7WQ4 7WQ3 7XJJ

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
GAL1 GALR1 Human Galanin A pKi 9.1 8.54 10.51 Guide to Pharmacology
GAL2 GALR2 Human Galanin A pKi 8.0 8.61 9.07 Guide to Pharmacology
GAL3 GALR3 Human Galanin A pKi 7.16 7.16 7.16 Guide to Pharmacology
GAL3 GALR3 Rat Galanin A pKi 7.28 7.28 7.28 Guide to Pharmacology
GAL2 GALR2 Rat Galanin A pKi 8.6 8.6 8.6 Guide to Pharmacology
GAL1 GALR1 Rat Galanin A pKi 9.22 9.54 9.85 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
GAL1 GALR1 Human Galanin A pIC50 9.57 9.73 9.89 Guide to Pharmacology
GAL2 GALR2 Human Galanin A pEC50 7.91 8.53 9.15 Guide to Pharmacology
GAL2 GALR2 Human Galanin A pIC50 9.29 9.29 9.29 Guide to Pharmacology
GAL3 GALR3 Human Galanin A pIC50 7.12 7.12 7.12 Guide to Pharmacology
GAL2 GALR2 Rat Galanin A pIC50 8.6 8.8 9.0 Guide to Pharmacology
GAL1 GALR1 Rat Galanin A pIC50 10.15 10.19 10.22 Guide to Pharmacology
GAL1 GALR1 Human Galanin A pIC50 10.1 10.1 10.1 ChEMBL
GAL2 GALR2 Human Galanin A pIC50 8.59 8.59 8.59 ChEMBL