galanin(1-16) (rat/mouse/pig)
SMILES | None |
InChIKey | FHTSPMGFAZMZJT-GDGJPEIESA-N |
Sequence | GWTLNSAGYLLGPHAI |
Chemical properties
Hydrogen bond acceptors | None |
Hydrogen bond donors | None |
Rotatable bonds | None |
Molecular weight (Da) |
Drug properties
Molecular type | Peptide |
Physiological/Surrogate | Surrogate |
Approved drug | No |
Database connections
Sankey plot
Compound is not listed as a drug.
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
GAL1 | GALR1 | Human | Galanin | A | pKi | 8.3 | 8.8 | 9.3 | Guide to Pharmacology |
GAL2 | GALR2 | Human | Galanin | A | pKi | 7.89 | 8.35 | 8.8 | Guide to Pharmacology |
GAL3 | GALR3 | Human | Galanin | A | pKi | 6.5 | 6.5 | 6.5 | Guide to Pharmacology |
GAL3 | GALR3 | Rat | Galanin | A | pKi | 7.05 | 7.17 | 7.3 | Guide to Pharmacology |
GAL2 | GALR2 | Rat | Galanin | A | pKi | 7.89 | 8.31 | 8.74 | Guide to Pharmacology |
GAL1 | GALR1 | Rat | Galanin | A | pKi | 8.05 | 8.54 | 9.02 | Guide to Pharmacology |
GAL2 | GALR2 | Mouse | Galanin | A | pKi | 7.93 | 7.93 | 7.93 | Guide to Pharmacology |
GAL1 | GALR1 | Mouse | Galanin | A | pKi | 8.66 | 8.82 | 8.99 | Guide to Pharmacology |
GAL1 | GALR1 | Human | Galanin | A | pKd | 8.49 | 8.49 | 8.49 | ChEMBL |
GAL3 | GALR3 | Human | Galanin | A | pKd | 6.5 | 6.5 | 6.5 | ChEMBL |
GAL2 | GALR2 | Human | Galanin | A | pKd | 8.3 | 8.3 | 8.3 | ChEMBL |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
GAL1 | GALR1 | Human | Galanin | A | pIC50 | 9.0 | 9.11 | 9.22 | Guide to Pharmacology |
GAL2 | GALR2 | Human | Galanin | A | pIC50 | 8.66 | 8.66 | 8.66 | Guide to Pharmacology |
GAL2 | GALR2 | Human | Galanin | A | pEC50 | 7.26 | 8.32 | 9.38 | Guide to Pharmacology |
GAL2 | GALR2 | Rat | Galanin | A | pIC50 | 7.88 | 8.2 | 8.52 | Guide to Pharmacology |
GAL2 | GALR2 | Rat | Galanin | A | pEC50 | 7.03 | 7.03 | 7.03 | Guide to Pharmacology |
GAL1 | GALR1 | Rat | Galanin | A | pIC50 | 9.57 | 9.57 | 9.57 | Guide to Pharmacology |