GPCRdb

CHEMBL224375

Agent/drug
Bioactivity

CHEMBL224375

SMILES	CN(C)c1ccnc2sc3c(=O)n(-c4ccc(C(F)(F)F)cc4)cnc3c12
InChIKey	BHDZUAZIRRYQON-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	6
Hydrogen bond donors	0
Rotatable bonds	2
Molecular weight (Da)	390.1

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

mGlu₁	GRM1	Rat	Metabotropic glutamate	C	pKi	8.10	8.10	8.10	ChEMBL

Showing 1 to 1 of 1 entry

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

mGlu₁	GRM1	Rat	Metabotropic glutamate	C	pIC50	7.50	7.50	7.50	ChEMBL
mGlu₁	GRM1	Human	Metabotropic glutamate	C	pIC50	7.50	7.50	7.50	ChEMBL

Showing 1 to 2 of 2 entries

CHEMBL224375

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.