CHEMBL228278


SMILES COc1ccc(S(=O)(=O)N[C@H]2CC[C@H](N3CCC(c4ccccc4OC4CC4)CC3)CC2)cc1OC
InChIKey JFRXSPVSGNWHOD-HZCBDIJESA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 9
Molecular weight (Da) 514.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1B ADA1B Human Adrenoceptors A pKi 6.88 6.88 6.88 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 7.96 7.96 7.96 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 7.47 7.47 7.47 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.88 6.88 6.88 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database