CHEMBL228912


SMILES OC1(c2ccccc2)CCN(C(c2ccccc2F)c2ccccc2F)CC1
InChIKey OIIFNPJMKAMCSP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 379.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 8.22 8.22 8.22 ChEMBL
δ OPRD Human Opioid A pKi 5.75 5.75 5.75 ChEMBL
κ OPRK Human Opioid A pKi 5.93 5.93 5.93 ChEMBL
μ OPRM Human Opioid A pKi 6.83 6.83 6.83 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database