CHEMBL2112961


SMILES O=C(CNC(=O)[C@@H]1CCCN1C(=O)CC(c1ccccc1)(c1ccccc1)c1ccccc1)NC[C@H]1CCCN(CC2CCCCC2)C1
InChIKey GVTZHKIAVNUTSV-GOJCVTOHSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 12
Molecular weight (Da) 648.4

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M5 ACM5 Human Acetylcholine (muscarinic) A pKi 5.7 5.7 5.7 ChEMBL
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 7.37 7.37 7.37 ChEMBL
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 8.66 8.66 8.66 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 7.89 7.89 7.89 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 6.82 6.82 6.82 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database