GPCRdb

CHEMBL228911

Agent/drug
Bioactivity

CHEMBL228911

SMILES	OC1(c2ccccc2)CCN(C(c2ccccc2Cl)c2ccccc2Cl)CC1
InChIKey	VYRHTEGFBOSTMB-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	2
Hydrogen bond donors	1
Rotatable bonds	4
Molecular weight (Da)	411.1

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

δ	OPRD	Human	Opioid	A	pKi	5.78	5.78	5.78	ChEMBL
κ	OPRK	Human	Opioid	A	pKi	6.20	6.20	6.20	ChEMBL
μ	OPRM	Human	Opioid	A	pKi	6.59	6.59	6.59	ChEMBL
NOP	OPRX	Human	Opioid	A	pKi	8.70	8.70	8.70	ChEMBL

Showing 1 to 4 of 4 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

NOP	OPRX	Human	Opioid	A	pEC50	6.65	6.65	6.65	ChEMBL

Showing 1 to 1 of 1 entry

CHEMBL228911

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV 0

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.