GPCRdb

CHEMBL231184

Agent/drug
Bioactivity

CHEMBL231184

SMILES	Cc1ccc(-n2c(C)ccc2-c2cc(Cl)ccc2OCc2ccc(F)cc2)cc1C(=O)O
InChIKey	YNGYDYOYWOAUDY-UHFFFAOYSA-N

Chemical Properties

Hydrogen bond acceptors	3
Hydrogen bond donors	1
Rotatable bonds	6
Molecular weight (Da)	449.1

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

EP₁	PE2R1	Human	Prostanoid	A	pKi	9.00	9.00	9.00	ChEMBL
EP₃	PE2R3	Human	Prostanoid	A	pKi	6.30	6.30	6.30	ChEMBL
EP₄	PE2R4	Human	Prostanoid	A	pKi	5.10	5.15	5.20	ChEMBL
TP	TA2R	Human	Prostanoid	A	pKi	7.80	7.80	7.80	ChEMBL

Showing 1 to 4 of 4 entries

Search:

Receptor					Activity				Source

Protein	Gene	Species	Family	Class	Type	Min	Avg	Max	Database

EP₁	PE2R1	Human	Prostanoid	A	pIC50	8.30	8.30	8.30	ChEMBL
EP₄	PE2R4	Human	Prostanoid	A	pIC50	4.80	4.80	4.80	ChEMBL
TP	TA2R	Human	Prostanoid	A	pIC50	7.40	7.40	7.40	ChEMBL

Showing 1 to 3 of 3 entries

CHEMBL231184

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Surrogate
Approved drug	No

Distribution across phases (no. indications)

Phase I 0

Phase II 0

Phase III 0

Phase IV

Database connections

ChEMBL_compound_ids PubChem GPCRdb

Compound is not listed as a drug.