CHEMBL212645


SMILES O=C(NCC1CCN(C2CCCC2)CC1)[C@H]1CCCN1C(=O)[C@@H]1C[C@@H](O)CN1C(=O)CC(c1ccc(F)cc1)(c1ccc(F)cc1)c1ccc(F)cc1
InChIKey SSQJHXZOEJZLAK-IZNNDHRXSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 10
Molecular weight (Da) 730.4

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M5 ACM5 Human Acetylcholine (muscarinic) A pKi 5.5 5.5 5.5 ChEMBL
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 7.32 7.32 7.32 ChEMBL
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 9.29 9.29 9.29 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 6.96 6.96 6.96 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 6.68 6.68 6.68 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database