CHEMBL213122


SMILES Cc1ccc(N2CCN(C(=O)[C@H](C)Cc3ccc(Cl)cc3)CC2)c([C@@H](N)CC(C)C)c1
InChIKey RZLPZBLBQNNVLZ-YKSBVNFPSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 441.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC1 MSHR Human Melanocortin A pKi 5.51 5.51 5.51 ChEMBL
MC5 MC5R Human Melanocortin A pKi 6.0 6.0 6.0 ChEMBL
MC3 MC3R Human Melanocortin A pKi 5.89 5.89 5.89 ChEMBL
MC4 MC4R Human Melanocortin A pKi 7.6 7.6 7.6 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MC4 MC4R Human Melanocortin A pIC50 6.24 6.25 6.25 ChEMBL