CHEMBL213709


SMILES CCN1CCC(CNC(=O)[C@H]2CCCN2C(=O)[C@@H]2C[C@@H](O)CN2C(=O)CC(c2ccc(F)cc2)(c2ccc(F)cc2)c2ccc(F)cc2)CC1
InChIKey AOYBULVQHCLRGS-VATRIRCNSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 10
Molecular weight (Da) 690.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M5 ACM5 Human Acetylcholine (muscarinic) A pKi 5.55 5.55 5.55 ChEMBL
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 7.04 7.04 7.04 ChEMBL
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 9.04 9.04 9.04 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 5.89 5.89 5.89 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 6.24 6.24 6.24 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database