hexocyclium


SMILES C[N+]1(C)CCN(CC1)CC(c1ccccc1)(C1CCCCC1)O
InChIKey ZRYHPQCHHOKSMD-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 317.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug Yes

Database connections

Sankey plot

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 7.6 7.6 7.6 Guide to Pharmacology
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 8.9 8.9 8.9 Guide to Pharmacology
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 8.3 8.3 8.3 Guide to Pharmacology
M5 ACM5 Human Acetylcholine (muscarinic) A pKi 8.4 8.4 8.4 Guide to Pharmacology
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 8.05 8.05 8.05 Drug Central
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 8.08 8.08 8.08 Drug Central
M1 ACM1 Rat Acetylcholine (muscarinic) A pKi 8.07 8.07 8.07 Drug Central
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 8.12 8.12 8.12 Drug Central
M5 ACM5 Human Acetylcholine (muscarinic) A pKi 8.08 8.08 8.08 Drug Central
M1 ACM1 Rat Acetylcholine (muscarinic) A pKi 8.6 8.6 8.6 Guide to Pharmacology
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database