CHEMBL213912


SMILES CN1CCN(C2=Nc3ccc(Cl)cc3Oc3ccccc32)CC1
InChIKey FSRSEANZUZHDHK-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 0
Molecular weight (Da) 327.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Human Histamine A pKi 6.99 7.58 8.22 ChEMBL
H4 HRH4 Human Histamine A pKd 7.14 7.66 7.97 ChEMBL
H2 HRH2 Human Histamine A pKi 5.06 5.06 5.06 ChEMBL
H1 HRH1 Human Histamine A pKi 8.08 8.1 8.11 ChEMBL
H3 HRH3 Human Histamine A pKi 5.04 5.04 5.04 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H4 HRH4 Human Histamine A pEC50 7.7 7.7 7.7 ChEMBL
H1 HRH1 Human Histamine A pEC50 8.17 8.17 8.17 ChEMBL