CHEMBL2146803


SMILES COCCN1CCC[C@@H]1Cn1nc(Cc2ccc(Cl)cc2)c2ccccc2c1=O
InChIKey KMFDXNUGIFDFHQ-LJQANCHMSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 7
Molecular weight (Da) 411.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Sankey plot

Compound is not listed as a drug.

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1B ADA1B Human Adrenoceptors A pKi 7.9 7.9 7.9 ChEMBL
H1 HRH1 Human Histamine A pKi 9.29 9.29 9.29 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 7.7 7.7 7.7 ChEMBL
H3 HRH3 Human Histamine A pKi 6.4 6.4 6.4 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database