CHEMBL234423


SMILES Cc1ccc(S(=O)(=O)N[C@H]2CC[C@@H](N3CCN(c4ccccc4OC(C)C)CC3)CC2)cc1Cl
InChIKey PNMMHGYXIWNCEE-SZPZYZBQSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 505.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1B ADA1B Human Adrenoceptors A pKi 6.78 6.78 6.78 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 7.96 7.96 7.96 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 7.96 7.96 7.96 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.22 7.22 7.22 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database