CHEMBL234474


SMILES COc1ccc(Cl)cc1S(=O)(=O)N[C@H]1CC[C@@H](N2CCN(c3ccccc3OCC3CC3)CC2)CC1
InChIKey HQURDNFFLCLLLC-ZRZAMGCNSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 9
Molecular weight (Da) 533.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1B ADA1B Human Adrenoceptors A pKi 6.22 6.22 6.22 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 7.72 7.72 7.72 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 7.32 7.32 7.32 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.23 6.23 6.23 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database